Amplifiers_and_Stimulators

Amplifiers and stimulators

The biological amplifier and stimulator product line was specially developed for the fields of biological and biomedical research (physiology, pharmacology, neurology). The primary design aspect of the amplifiers and stimulators was the simple management of the measurement units and that they would easily fit to the methodologies. Furthermore, it was considered that any hardware/software system used in this area would be able to receive the signals of each unit. Therefore, the measuring and stimulating units are manufactured and sold in one-, two- and four-channel design, for similar and complex measurement functions.

DC bridge amplifier

The unit was developed to receive and amplify the signals from a force/displacement or pressure sensor (e.g. invasive blood pressure transducers, etc.). It is a guaranteed low -noise design with high filtration level.

Specification:

Amplification: x 10 000, continuously adjustable
Bandwidth: DC, 200Hz*
Calibration levels: GND, 1V (for the adjustment of the signal processing unit)
Bridge voltage: +3V DC*
Offset adjustment: ±6V related to the output
Display: ±LED Bar
Filtering: OFF, 3Hz, 10Hz, 40Hz, (80dB high-pass filter)
Input impedance: 10MW symmetric
Output impedance: 100W asymmetric
Input connector: 9-pole D-SUB (Cannon)
Output connector: 6,3 Jack socket
Power supply: 110V or 220V, 50/60 Hz
* other desired value can be set, but requires prior consultation.

DC bridge amplifier

Available models:

EXP-SG-1 DC bridge amplifier (1-channel)
EXP-SG-2 DC bridge amplifier (2-channel)
EXP-SG-4 DC bridge amplifier (4-channel)

Optional accessories:

SEN-03-XX Force/displacement transducer
SEN-04-XX Implantable force/displacement transducer
SEN-02 Invasive blood pressure sensor

DC bridge amplifier designed for invasive blood pressure measurement

The unit has been designed to measure specifically arterial, venous or cardiac ventricular pressure. Accordingly, it has internal calibration options, and can be connected to any blood pressure sensor in the market (default SEN-02). It is a guaranteed low -noise design with high filtration level.

Specification:

Amplification: x 1 000
Bandwidth: DC, 200Hz
Calibration levels: GND, 10Hgmm / 100Hgmm (for the adjustment
of the signal processing unit)
Balance adjustment: ±300Hgmm / 3Hgmm related to the input
Bridge voltage: +5V DC*
Offset adjustment: ±6V related to the output
Display: ±LED-BAR
Input impedance: 10MW symmetric
Output impedance: 100W asymmetric
Input connector: 9-pole D-SUB (Cannon)
Output connector: 6,3 Jack socket
Power supply: 110V or 220V, 50/60Hz
* other desired value can be set, but requires prior consultation

DC bridge amplifier designed

Available models:

EXP-EXT-1 Broadband amplifier (1-channel)
EXP-EXT-2 Broadband amplifier (2-channel)
EXP-EXT-4 Broadband amplifier (4-channel

Optional accessories:

Mini banana plug for symmetric/asymmetric connection (3pcs plug/pack)
SEN-15-XX Ag/AgCl electrodes
Glass electrodes
Metal electrodes

Amplifier for measuring ECG (from surface leads, for standard I-II-III)

The unit was specifically designed for standard (I-II- III) ECG measurements with derived parameters. It has 1 mV internal calibration. The input time constants and resistance, as well as the amplification and the frequency transmission make possible the measurement of any species (mouse, rat, dog, pig, etc.). The unit has low noise level and features a high-pass notch filter, and input diode defibrillator protection.

Specification:

Amplification: x 1 000
Bandwidth: DC, 1kHz*
Calibration levels: GND, 1mV (for the adjustment of the signal processing unit)
Filtering: 50Hz / 80dB
Input impedance: 100kW symmetric
Output impedance: 100W asymmetric
Input connector: 15-pole D-SUB (Cannon)
Output connector: 9-pole D-SUB (Cannon)
Power supply: 110V or 220V, 50/60Hz

Available models:

EXP-ECG-1 ECG amplifier I, II, III (1-channel)
EXP-ECG-2 ECG amplifier I, II, III (2-channel)
EXP-ECG-4 ECG amplifier I, II, III (4-channel

Amplifier for measuring ECG

Optional accessories:

CAB-062 Four-lead body surface patient cable with banana plug (2,5m)
CAB-063 Ten-lead body surface patient cable with banana plug (1,5m)
CAB-064 Four-lead body surface patient cable with banana plug (1,5m)
CAB-067 Four-lead implantable patient cable

Broadband amplifier for extra- and intracellular measurements

The unit is a broadband, low-noise amplifier, which is suitable for the amplification of intra-/extracellular potentials in the in-vivo conscious, in-vivo anesthetized and in-vitro tissue slice models (e.g.: cardiac map, nerve evoked potentials, etc. ). The high quality low/high-pass filters allow to mark the bands of the basic physiological signs (EEG, ECG, EMG, EGIG, etc.) and through which also the accurate transfer of the wave characteristics. The unit consists of two main parts, the low –noise, high input impedance pre-amplifier and the end-amplifier, which contains the high-slope band-pass and notch filters.

Specification:

Amplification: x102; 103; 104, calibrated with a pre-amplifier
Bandwidth: DC, 20kHz
Noise: CMMR<120dB
Calibration levels: GND, 100% (for the adjustment of signal processing unit)
Offset adjustment: ±1V related to the input
High-pass filter: DC, 0.05; 0.1; 0.5; 1; 5; 10; 50;
100Hz / 80dB
Low-cut filter: DC, 0.05; 0.1; 0.5; 1; 5; 10; 50;
100Hz / 80dB
Notch filter: 50Hz 80db
Input impedance: 10MΩ symmetric / 109Ω asymmetric
Output impedance: 100Ω asymmetric
Input connector: Mini banana socket (2mm)
Output connector: 6,3 Jack
Power suppl: 110-220 V/12 V 1A DC adapter

Broadband amplifier

Available models:

EXP-EXT-1 Broadband amplifier (1-channel)
EXP-EXT-2 Broadband amplifier (2-channel)
EXP-EXT-4 Broadband amplifier (4-channel

Optional accessories:

Mini banana plug for symmetric/asymmetric connection (3pcs plug/pack)
SEN-15-XX Ag/AgCl electrodes
Glass electrodes
Metal electrodes

Amplifier for measuring temperature

The unit is suitable for 0,1°C accuracy continuous temperature measurement of gaseous, liquid and solid substances depending on the connected sensor. Any crystalline or semiconductor sensor can be connected to the unit (thermistor, Pt100, etc.). The high-speed data communication is provided by the set up speed and the 3- digit LED display. In case of sensor replacement, the accuracy of the unit is ensured by the two-point calibration procedure.

Specification:

Measurement range: 20–50OC (expandable: 0–100OC)*
Measuring accuracy: 0,1OC
Display: 3 digit, LED
Internal calibration: GND; 45OC=450mV
Output: 10mV/°C
Input connector: 6,3 Jack
Output connector: 6,3 Jack
Power supply: 110V or 220V, 50/60Hz
* requires prior consultation

Available models:

EXP-TH-1 Temperature meter amplifier (1-channel)
EXP-TH-2 Temperature meter amplifier (2-channel)
EXP-TH-4 Temperature meter amplifier (4-channel)

Amplifier for measuring temperature

Optional accessories:

SEN-06-XX Stick thermometer
SEN-07-XX Temperature sensor for organ perfusion or nerve tissue slice systems
SEN-09-XX Catheter temperature sensor
SEN-11-XX Body surface temperature sensor

Amplifier for measuring temperature

The unit can only be operated on anesthetized species. The external diameter of the tracheal cannula developed to this unit, determines on what species the unit can be used. The present design allows four applications (rat, rabbit, dog, pig). The removable thermo sensor is placed in the cannula, which measures the respiratory rate based on the temperature difference of the air coming from the lungs. The sensor is interchangeable and can be connected to any tracheal cannula. In case of failure the replacement can be
performed without calibration.

Specification:

Measurement range: 2–200 respiratory rate/min
Calibration: GND; 100%
Sensitivity: 1V=100%=100 respiratory rate/min
Display: Respiratory rate display with LED diode
Input connector: 6,3 Jack
Output connector: 6,3 Jack
Power supply: 110V or 220V, 50/60Hz

Available models:

EXP-LH-1 Respiratory rate measurer amplifier
(1-channel) with SEN-08-XX sensor

Amplifier for measuring temperature

Amplifier for intracellular measurements

The amplifier is primarily suitable for the examination of the heart cells, but it can also be used for intracellular measurement of other organs (e.g.: spinal cord, brain, etc.). The amplifier is characterized by large input resistance (1012Ώ) with a low noise capacity and zero level stability. To achieve these favourable parameters we have chosen linear amplifier solution with reference artificial ground solution. The services of the amplifier (capacity compensation, resistance measurement, DC electrode contact potential cancellation) are controlled by the fixed resistance (1Ώ) reference artificial ground. The amplifier consists of two units; the” INTE” large input resistance pre-amplifier, which can be directly connected with the electrode sleeve (types: WPI, Harvard, Clark etc. ), and the end-amplifier, which includes the previously described circuit elements and provides the connection to data visualizing, storing and evaluating hardware/software systems.

Specification:

Input resistance: 1012 Ω asymmetric
Input capacity-compensated: 0–25pF
Input leaking current: ±10pA
Input voltage range: ±5V
Amplification: x1, x10
Output resistance: 100Ω, asymmetric
Reference artificial ground: 1Ω
DC positioning (Bucking): ±300mV
Resistance measurement: 1MΩ–100MΩ
Calibration signal: 100mV/200Hz square wave
Display: 3,5 digit
Power supply: 110V or 220V 50Hz

Amplifier for intracellular measurements

Available models:

EXP-INT-1 Intracellular amplifier (1-channel)
EXP-INT-2 Intracellular amplifier (2-channel)
EXP-INT-4 Intracellular amplifier (4-channel)

Optional accessories:

SEN-27 Ag/AgCl reference electrode
SEN-12-12 Ball-mounted manipulator (360°movement, self-righting platinum stimulating electrode)
MAN-09-XX Three-plane 1μmm precision manipulator with magnetic base
ISO-03-XX Vibration-free workstation with organ bath (5 or 10ml) with buffer or pump
ISO-01-XX Externally thermostated horizontal organ bath (5 or 10ml)
FAR-01-01 Faraday cage (80x50x120cm)
Glass capillaries

MCU stimulator controlling unit

MCU controlling unit is designed for programming the stimulators. It cannot be purchased separately, supplied only with stimulators.

Specification:

Synchronous output signals:
Output signal level: 0 ±5V (TTL-levels)
Max. load ability: 1 TTL inlet
Length of synchronous signals: 25μsec
Active signal edge: Falling edge

Timing parameters of the impulse:

period time(PP): 500 μsec–999 μsec
delay (DE): 0,1 μsec–999 μsec
width (PW): 10 μsec–999 μsec
train delay (TD): 10 μsec–999 μsec
number of trains: 1–999

MCU stimulator controlling unit

Output connector: 9-pole D-SUB (Cannon)
Programming input connector: USB, 9-pole D-SUB (Cannon, RS232)
Power supply: 110V or 220V, 50/60Hz

Available models:

EXP-MCU stimulator controlling unit*
*it cannot be purchased separately, supplied only with stimulators

Non-isolated stimulators

The devices (EXP-ST-0X products) are produced in one-, two- and four-channel designs. The mutual characteristics of the devices are the identical stimulus impulse and performance parameters. They are without isolation, operating from the electrical system. The MCU controlling unit is built into one rack with the one- or two-channel stimulators and supplied separately in case of four-channel stimulator.

Specification:

Max. output performance: 10 W/ch
Impulse rise/fall: 10μsec/100V
Voltage output:

Max output voltage ±10V, ±100V
Max. current load: ±100mA
Output protection: Short-circuit protected

Non-isolated stimulators

Current output:

Max. output current: ±10mA, ±100mA
Max output voltage: ±100V
Output protection: Short-circuit protected

Output connector: Banana plug (4mm)
Input connector: 9-pole D-SUB (Cannon)
Power supply: 110V or 220V, 50/60Hz

Available models:

EXP-ST-01 One-channel non-isolated stimulator with built-in MCU controlling unit
EXP-ST-02 Two-channel non-isolated stimulator with built-in MCU controlling unit
EXP-ST-04 Four-channel non-isolated stimulator with MCU controlling unit

Battery-operated, isolated stimulators

The devices (EXP-ST-AX products) are produced in one-, two- and four-channel designs. The mutual characteristics of the devices are the identical stimulus impulse and performance parameters. They are isolated, operating from rechargeable batteries (accumulators). The MCU controlling unit is built into one rack with the one- or two-channel stimulators and supplied separately in case of four-channel stimulator.

Specification:

Max. output performance: 2,5 W/ch
Impulse rise/fall: 10μsec/50V
Voltage output:

Max. output voltage: ±5V, ±50V
Max. current load: ±50mA
Output protection: Short-circuit protected

Current output:

Max. output current: ±5mA, ±50mA
Max output voltage: ±50V
Output protection: Short-circuit protected

Battery-operated, isolated stimulators

Output connector: Banana plug (4mm)
Input connector: 9-pole D-SUB (Cannon)
Power supply: 110V or 220V, 50/60Hz

Available models:

EXP-ST-A1 One-channel battery-operated, isolated stimulator with built-in MCU controlling unit
EXP-ST-A2 Two-channel battery-operated, isolated stimulator with built-in MCU controlling unit
EXP-ST-A4 Four-channel battery-operated, isolated stimulator with MCU controlling unit

High-current stimulator

The unique high-current device is produced only in one-channel design. The mutual characteristics of the device are the identical stimulus impulse and performance parameters. They are without isolation, operating from the electrical system. The MCU controlling unit is built into one rack with the one- or two-channel stimulators and supplied separately in case of four-channel stimulator.

Specification:

Max. output performance: 50 W
Impulse rise/fall: 10μsec/100V
Voltage output:

Max. output voltage: ±10V, ±100V
Max. current load: ±500mA
Output protection: Short-circuit protected

Current output:

Max. output current: ±10mA, ±100mA
Max output voltage: ±100V
Output protection: Short-circuit protected

Output connector: Banana plug (4mm)
Input connector: 9-pole D-SUB (Cannon)
Power supply: 110V or 220V, 50/60Hz

High-current stimulator

Available models:

EXP-ST-P1 One-channel high-current stimulator with built-in MCU controlling unit

Media

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Amplifiers_and_Stimulators